Killah has three children, all of whom have started their careers in music. His son, Infinite Coles, is a singer, whereas his sons Supreme Coles and Sun God Coles are rappers.
He grew up in a cramped apartment in the Stapleton project among several siblings. Two of his siblings suffered from muscular dystrophy. Killah was raised by a single mother in Staten Island, New York, USA.
Ghostface is a Muslim as the rapper converted to Islam in 2004. He filed a lawsuit against Universal Music in August 2011 for unpaid royalties.