The answer is no; Brigitte Macron is not sick now and has not been diagnosed with any illness.

According to reports, she tested positive on December 24, 2020, with minor symptoms but was negative six days later. 

She tested positive after her husband, French President, was placed in isolation for a week after testing positive.

She lived at the official presidential house, the Elysees palace, at that time, while he worked at a property outside of Paris.

Her office stated that the information about her illness was not made public since it had no bearing on her public agenda at the time.

Furthermore, they declared that she has subsequently made a full recovery.