Jimmy Garoppolo, whose real name is James Richard Garoppolo, was born to his parents, father Tony Garoppolo Sr., a retired electrician, and mother, Denise Garoppolo.

Garoppolo is the third of four sons born to his parents. His older brother Tony Garoppolo Jr. is an architect, and his second brother, Mike Garoppol,o is a teacher, and his younger brother is Billy Garoppolo.

He has a tight-knit, big Italian family, as his parental grandparents, Rose and Anthony Garoppolo, were Italian immigrants.

On the other hand, his maternal grandparents, Harriet D. Seidel and Theodore J. Malec, were of German and Polish descent.