On August 26, 1988, Wayne Simmonds was born in the city of Scarborough, in the province of Ontario.
He is the third of four sons and one daughter that Cyril Simmonds and Wanda Mercury-Simmonds have together. The couple also has a daughter.
His ancestors came from North Preston, in the province of Nova Scotia. Simmonds had stated that he was primarily a fan of the Detroit Red Wings when he was a child, even though he grew up in the Toronto region. When he was little, Sergei Fedorov was his all-time favorite player.
When Simmonds was in the third grade, he had to write a paper for career day. In it, he expressed his desire to become a professional hockey player. Even though his teacher was discouraging, Simmonds did not alter what he had written.
Most of Simmonds’ time was spent playing minor hockey was spent in the east end of Toronto, where he was a member of many A and AA hockey teams, including the Minor Midget Toronto Aces in the 2003–2004 season of the Greater Toronto Hockey League (GTHL).
Simmonds jumped to the AAA level for the first time in 2004–05 with the Toronto Jr. Canadiens midgets of the Greater Toronto Hockey League (GTHL). This occurred after numerous GTHL AAA players went to junior hockey the previous summer.