Elise Mertens was born on 17 November 1995 to her parents, Liliane Barbe and Guido Mertens. Besides Elise, the couple has a daughter named Lauren Mertens.

Mertens’ mother is a teacher who has been teaching her students for a long time. Her father is a carpenter who prepares furniture for churches.

Though her birth country is Belgium, her ethnicity is not known.

Since engaging in sports at an early age somehow created disturbances in her studies, she was homeschooled. She enjoyed studying and learning various languages, including French, English, and Dutch/Flemish.

Her family has always been the supporter of the player. They have always cheered Mertens to move forward.