No, Jesse James Keitel is not a transgender man but rather a non-binary person who addresses herself with she/her pronouns.

Keitel has always denied labelling herself as a man or a woman. 

Instead, she has opted to be recognized as a non-binary person without associating herself with being a man or a woman.

Similarly, the 28-year-old actress prefers to label herself as ‘her’ while using her as a pronoun.

From this, we can get a hint that she rather likes to be associated with the female gender to some degree rather than a man.