Scott began to paint seriously in 1999 under the direction of professor and mentor Leland Wallin. In 2002, Scott opened an art gallery in Concord, North Carolina. He paints many self-portraits that he says reveal and represent “states of emotions in [his] life.” He has also developed a unique methodology in his portraits by using a narrative approach. He creates individual characters who, in later works, are the subject of various events involving multiple figure paintings. Scott’s unique portraits are much like a story book. In addition to oil-on-canvas portraits, Scott is also an accomplished printmaker. He returns to East Carolina University (ECU) as the need arises in order to create special prints in celebration of events relating to his band, The Avett Brothers. Scott specializes in creating relief prints, a skill that he acquired at ECU under the direction of professor Michael Elhbeck. These prints are renowned among the fans of The Avett Brothers both for their sentimental and artistic value. Scott’s artwork was featured at the Envoy Gallery in New York City from July through August in 2008. Scott’s work is also featured in a special exhibit titled Scott Avett: INVISIBLE at the North Carolina Museum of Art in Raleigh North Carolina from October 26, 2019–January 19, 2020.
Avett painted the cover artwork for By the Way, I Forgive You, the 2018 album of long-time friend Brandi Carlile.